Future work is needed to compare the effect of tirzepatide and semaglutide on other key end points (eg, reduction in major adverse cardiovascular events)
Cholecystokinin-33, but not cholecystokinin-8 shows gastrointestinal site specificity in regulating feeding behaviors in male rats
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Tirzepatide should be administered subcutaneously in the abdomen, thigh, or upper arm, with site rotation to prevent lipohypertrophy or lipoatrophy that can impair absorption
First characterised by Professor Predrag Sikiric and colleagues at the University of Zagreb in the early 1990s, BPC-157 has since become one of the most widely studied peptides in preclinical research, spanning gastrointestinal biology, musculoskeletal repair, neuroprotection, and cytoprotective signalling