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Improved motor co-ordination in Scopoletin treated park 13 flies To test whether the improvement in neuronal abnormalities translated to rehabilitation of aberrant movement phenotypes including motion slowness, difficulties with gait and balance, we utilized the negative geotactic and phototactic behavior of Drosophila flies

doi: 10.1210/clinem/dgad361

Glossario dei termini principali Citocromo P450 (CYP450) : famiglia di enzimi, soprattutto epatici, che metabolizza molti farmaci di sintesi

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Post-treatment assumptions had a limited impact on the cost-effectiveness results, with reversion to no-treatment progression resulting in an ICER of 12,669/QALY, while accelerated weight regain to baseline within 1 year yielded an ICER of 12,410/QALY