Jianping W, Xuelian Z, Anjiang W, Haiying X
In a randomized placebo-controlled trial in 78 women with moderate-to-severe menopausal symptoms, 190 mg per day of combined hops and soy extracts for 12 weeks resulted in a 20.16-point reduction in menopausal symptom scores, compared with a 14.80-point reduction in the placebo groups, and no changes in endometrial thickness or hormone profiles were detected
In addition, when circulating L-carnitine concentration increases, as in the case of oral supplementation, renal reabsorption of L-carnitine may become saturated, resulting in increased urinary excretion of L-carnitine (5)
The chemical name of levocarnitine is (R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium, inner salt
Another potential mediator is the imbalance of endogenous anabolic hormones (e.g., testosterone, insulin-like growth factor 1) and catabolic factors, such as glucocorticoids and myostatin [9, 11]