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These fasted mutants also exhibited physiological changes similar to those observed in wild-type fasted animals, including reduced body size and enhanced motility (Supplementary Fig

Foundational evidence here comes from animal models showing that CoQ10 supplementation can restore oocyte mitochondrial function in aged mice, 3 with subsequent human trials beginning to map the same pathway in clinical settings (see CoQ10 section below)

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Throughout the 14 days of observation after oral administration, there were no deaths and clinical abnormal changes observed in the treated mice, which were dosed at 1500, 3000, 6000 mg of the T1 compound per kilogram of body weight

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