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DNA fragments of SLC7A11 (-1498 to -123) and SLC3A2 (-1407 to -120) promoter regions were amplified from MDA-MB-231 genomic DNA by PCR and subcloned into the pGL3-luc plasmid

Additionally, the peptide might have reactivated the apoptosis pathway, a type of programmed cell death crucial for removing faulty cells, as evidenced by activity in caspases 3 and 7, which are enzymes that play key roles in apoptosis

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L-asparaginase can deplete plasma Gln and is widely utilized as an adjuvant therapy in lymphoma (106)

Multiple proinflammatory factors secreted by the SASP have been shown to play key roles in driving aging