It has an hepatic metabolism, mainly because of the glucuro-conjugation of the molecule, with the formation of inactive metabolites
Even tendons damaged by corticosteroid use, notorious for impairing healing, showed restoration of structural and functional integrity with BPC-157 administration
2006 DOI: 10.1002/jor.20096 PMID: 16583442 Read on PubMed Current Pharmaceutical Design Fistulas Healing
This can show up as symptoms such as delayed growth and development (failure to thrive), regression in neuromotor skills (such as losing the ability to roll over or grasp objects), failure to maintain eye contact (even in an infant who previous could do so), general muscle weakness, lethargy, excessive sleepiness, feeding difficulties, and even brain shrinkage
Because of that design, AOD 9604 is positioned by some clinics and wellness practices as a fat-burning peptide rather than a full hormone replacement