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Abbreviations AA Alopecia Areata NAC N -acetylcysteine System XC Cystineglutamate transporter exchange transport system EAAT3 Excitatory amino acid transporter 3 ASCT Alanineserinecysteine transporter GSH Glutathione Hcy Homocysteine CBS Cystathionine--synthase CSE Cystathionine--lyase GGT -Glutamyl transpeptidase ROS Reactive oxygen species MT Metallothionein Nrf2 Nuclear factor erythroid 2-related factor 2 PTEN Phosphate and tensin homolog deleted on chromosome 10 PTP Protein tyrosine phosphatase CoA Genome-wide association studies CoA Coenzyme A TCA Tricarboxylic acid TRP-1 Tyrosinase-related protein 1 TRP-2 Tyrosinase-related protein 2 GPX4 GSH peroxidase 4 mTORC1 Mechanistic target of rapamycin complex 1 Rag Recombination activating gene 4EBPs Eukaryotic initiation factor 4E-binding proteins -glucys Amino-acid transporter solute carrier family 7 member 11(SLC7A11) -glutamatecysteine INF- Interferon HHcy Hyperhomocysteinemia CRH Corticotropinreleasing hormone Author contributions Wen Xu, Xie Bo, Dongfan Wei and Xiuzu Song drafted the manuscript and prepared the figures

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Osteoporosis High blood concentrations of homocysteine may affect bone remodeling by increasing bone resorption (breakdown), decreasing bone formation, and reducing bone blood flow

You simply reconstitute one vial and inject the prescribed dose