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Full reconstitution guide Advanced calculator Dosing & Reconstitution Guide A single practical dilution with accurate once-daily dosing, step by step Standard / Gradual Approach (5 mL = 100 mg/mL) Reconstitute: Add 5.0 mL bacteriostatic water to one 500 mg vial final concentration 100 mg/mL (1 unit = 1 mg)

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PKC, pharmacokinetic

Rationale for metabolic state-driven as an approach for restoring susceptibility in multidrug-resistant pathogens Recent findings demonstrate that the local environment modulates bacterial drug uptake and other aspects of bacterial metabolism 10,11,16,17,18