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doi: 10.1016/j.lfs.2004.11.030

Januvia requires dose adjustment when eGFR falls below 45 mL/min/1.73m, with a reduced dose of 50mg daily for moderate impairment (eGFR 30-45) and 25mg daily for severe impairment (eGFR below 30)

Nausea, vomiting and other gastrointestinal effects are the most commonly reported concerns, and for many people the side effect profile matters as much as the weight loss results when deciding which medication to try

Patients can expect to lose 10-15% of their body weight (up to 17.4%) over approximately 68 weeks

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