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*Eligible patients with a BMI of 30, or 27 with comorbidities, lost an average of 19% of their body weight (-33.6 lbs) in a 68-week clinical trial evaluating 2.4 mg semaglutide, when combined with a reduced-calorie diet and increased physical activity
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SUSTAIN-6 demonstrated a significant reduction in HbA1c levels and body weight compared to placebo, along with a reduction in cardiovascular risk
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Zepbound and Mounjaro (tirzepatide): why the FDA put a warning on the label Tirzepatide has 2 active ingredients: GLP-1 / GIP dual agonists and the FDA labels for both Mounjaro (the diabetes formulation) and Zepbound (the chronic-weight-management formulation) carry an explicit drug-interaction note about oral hormonal contraceptives
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