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It is associated with increased BDNF activity, improved cerebral blood flow, and enhanced cognitive resilience

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In documented animal work it was dispersed in a mixed organic vehicle (for example a DMSO / PEG-300 / Tween-80 / saline blend) and dosed by mass [3]

The analysis published in 2019 used a slightly different dataset, based on the intent-to-treat population in which missing data were imputed using multiple imputation based on retrieved dropout analysis [15]

This does not necessarily increase therapeutic benefit proportionally because tissue binding sites saturate