Interestingly, GLP-1 is also produced in a smaller amount in the brainstem, specifically the nucleus of the solitary tract
Kinlen D, Cody D, OShea D
Higher HbA1c has also been consistently associated with cardiovascular disease risk, worse cognitive aging, increased liver fat, early kidney impairment, higher inflammation, reduced fertility, and higher mortality risk
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Many of the antioxidant mechanisms are encoded by genes that contain ARE (antioxidant response elements), which are activated by the increase of free radicals [69]