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Other common adverse effects include diarrhea, constipation, dyspepsia, abdominal pain, and decreased appetite [47]

Bekdeser, B., zyrek, M., Akyz, E., et al

Melanotan-2: The Shotgun Approach MT-2 hits the same MC1R receptor but also activates MC3R, MC4R, and MC5R : MC1R Melanin production (tanning) MC3R Energy homeostasis, cardiovascular function MC4R Sexual arousal, appetite regulation, erectile function MC5R Exocrine gland function, sebaceous secretion This non-selective binding is why MT-2 causes the "side effects" that many users actually seek out particularly the libido and appetite suppression effects

Retatrutide is a triple GIP/GLP-1/glucagon agonist