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Intended setting: Laboratory research and analytical use

The molecular details of precise regulation of the cellular circadian clock are outside the scope of this review

Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice

Materials and Methods Human sample processing All human tissue experiments were carried out according to the University of Ottawa and Mount Sinai Hospital Research Ethics Board guidelines and approval (University of Ottawa REB protocol# H08-17-08, Mount Sinai Hospital REB protocol# 20-0037-E)