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Recently, we found that inhibiting ferroptosis with Fer-1 delays cyst growth in both rapidly progressive and slowly progressive ADPKD mouse models, while inducing ferroptosis with its inducer erastin promotes cyst growth in these mouse models (270)

doi: 10.1038/s41598-017-17715-1

However, during ovarian aging, defects in PINK1/Parkin-mediated mitophagy further promote ferroptosis and apoptosis (Khan et al., 2023