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The Endocrine Society's 2020 position statement on peptide therapeutics emphasizes that "the absence of Phase I dose-escalation data for novel peptides like BPC-157 means that any dose recommendation is extrapolated, not validated, and clinicians should err on the side of the lowest effective dose" 19

J Biol Chem 285(34):2613526148 Wilkins HM, Marquardt K, Lash LH, Linseman DA (2012) Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione

A novel antioxidant and antimicrobial peptide from hen egg white lysozyme hydrolysates

Visual indicators The appearance of lyophilized peptide provides the first clue about its condition