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Macrophage polarization, the process by which macrophages adopt either a pro-inflammatory (M1) or anti-inflammatory (M2) state, is crucial in influencing tumor growth, immune evasion, and resistance to therapies in ovarian cancer

Additionally, a novel biomarker, Collagen type XI alpha 1 (COL11A1) (56), has been found to induce platinum resistance by upregulating fatty acid metabolism in ovarian cancer through its binding to discoid domain receptor 2 and activating Src-Akt-AMPK signaling

They work best when combined with adequate protein intake (at least 0.8 to 1.0 grams per kilogram of body weight daily, often more), regular resistance training to preserve muscle mass, and attention to overall nutrition

Your healthcare provider will discuss potential side effects and monitor your progress throughout treatment

Sahu, A., Jeon, J., Lee, M., Yang, H