These mice were then randomly divided into eight groups (seven mice per group): a vehicle group, an MXD (MXD) group, an imidocarb (1%) group, a profavine (1%) group, an abemaciclib (1%) group, an aminoacridine (1.0%) group, an aminoacridine (0.3%) + MXD (0.3%) group, and an aminoacridine (1.0%) + MXD (0.3%) group
Body weight considerations The Phase 2 clinical trial used fixed doses regardless of body weight
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