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Tesamorelins metabolic effects
Additional support comes from case series and long-term follow-ups by prolotherapy practitioners
Reported effects are associated with the acute GH pulse: head rush, transient paresthesia in hands and feet, mild water retention, injection-site irritation, and occasionally a mild bump in appetite (much less than GHRP-6 or GHRP-2)
Two practical considerations apply: the compound must be LAL-tested before use in live cell systems to rule out endotoxin interference, and researchers running multi-day assays should account for dose-dependent IGF-1R downregulation by considering pulsed dosing or periodic compound replenishment
Interestingly, clinical isolates, and other Candida spp., can cause infection independent of filamentation or toxin production
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