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Additionally, certain medical interventions, particularly cancer immunotherapies using immune-checkpoint inhibitors (ICIs), have been reported to precipitate autoimmune thyroiditis by enhancing T-cellmediated immune responses and breaking self-tolerance (Barroso-Sousa et al

Reported side effects may include: Nausea Flushing Appetite suppression Blood pressure changes Darkening of freckles or moles Potential melanoma concerns Excessive UV exposure may still increase the risk of skin damage and skin cancer

mechanical : Having to do with the devices that move, including tools, engines and other machines (even, potentially, living machines)

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