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doi:10.1038/s41591-023-02235-5 Bodnaruc AM, Prudhomme D, Blanchet R, Giroux I

Although these vitamins share some characteristics, they all have unique functions and are needed in different amounts

Shifts in hormones, metabolism, and body composition can make this transition especially difficult for weight management

Promising safety profile: Early trials report tolerability comparable to incretin-based agents, though higher doses are associated with GI side effects (nausea, diarrhea, vomiting, constipation) Clinical Advantage over Others (Clinical Trial Evidence) Phase 2 obesity studies: At 48 weeks, retatrutide delivered weight reductions up to 24%, far exceeding results reported for monotherapy GLP-1 agents

Staying hydrated is another key factor in promoting healing