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However, individuals who have type 2 diabetes alongside a need to minimise weight gain or promote weight loss may benefit from GLP-1/GIP therapy and its dual impact on type 2 diabetes management and weight loss

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Useful safety observations often include: Local tolerance: redness, irritation, swelling, or tenderness at the administration site Acute post-dose observations: changes in behavior, appetite, activity, or visible discomfort during the expected response window Pattern effects over time: whether repeated dosing appears to change tolerability or response consistency Protocol drift: missed timing windows, inconsistent preparation, or undocumented deviations that can confuse safety interpretation How dosing logic affects safety interpretation The why behind dosage matters most

However, the ability of SDF-1 to promote repair involves both inflammation, angiogenesis and fibrosis, which could theoretically have adverse effects on the course of many of the macrovascular and microvascular complications of diabetes [18]

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