In experimental wound healing models, TB-500 treatment increases capillary density by 40-50% while improving functional blood flow restoration, demonstrating translation of cellular angiogenic activity into meaningful tissue-level perfusion benefits
doi: 10.1124/pr.115.011395 8 DruckerDJ
Temporary increase in body temperature from heightened metabolic activity
3 While other diabetic treatment options exist, including low carbohydrate diets, physical activity, and other medication options, GLP1 receptor agonists can serve as a powerful tool for diabetic management in individuals who have been unable to achieve desired glycemic control using such options
Furthermore, Boehringer Ingelheim and Zealand Pharma A/S announced the initiation of phase 2 clinical trial for its dual-acting GLP-1/glucagon receptor agonist, BI 456906 in September 2019