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Sermorelin Sermorelin is a synthetic version of a naturally occurring hormone called growth hormone-releasing hormone (GHRH)

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Tirzepatide is a dual GLP-1 and GIP receptor agonist , meaning it mimics two hormones, working even more comprehensively to manage appetite and metabolism

Consistent with this, GLP-1R agonism decreases a variety of reward behaviors in rodents, including the motivation to lever press for food reward in an operant conditioning test [746], alcohol intake [747,748], alcohol seeking behavior [747], amphetamine-induced conditioned place preference (Amp-CPP) [748], and hedonic feeding [748]

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