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While more research is needed to better understand this relationship, patients should be aware of potential symptoms and speak with their eye doctor about any vision changes

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Agents such as liraglutide (3.0 mg daily) and once-weekly semaglutide have been approved for obesity treatment, achieving weight reductions of approximately 515% in many patients Highdose GLP-1RAs significantly reduce body weight by suppressing appetite and calorie intake [234]

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In this population, GLP-1 medications are generally safe, but baseline metabolic rate is already elevated, and the combination requires skilled medical oversight

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Microglia and macrophages play an important role in acute neuroinflammation

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