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Funding This work was supported by grants from Conselho Nacional de Desenvolvimento Cientfico e Tecnolgico (CNPq, funding number 302961/2021-6 to C.M., 308192/2021-4 to M.L.C.) and Fundao de Apoio Pesquisa do Estado do Rio de Janeiro (FAPERJ, funding number E-26/203.930/2024 to C.M., E26/204.077/2024 to M.L.C.)

The combination produces a sustained, physiologically normal pulsatile GH release pattern that builds in effect over weeks and months

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