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It plays a central role in transporting fatty acids into cells, where theyre converted into usable energy

Briefly, mice exhibiting the FUSALS phenotype (characterized by FUS translocation from the nucleus to the cytoplasm) demonstrated longer lifespan, reduced disease severity and improved histological patterns when intracellular HSPA1A was overexpressed (Piavchenko et al., 2024

This accumulation depletes the other types of folate required for purine and thymidylate synthesis, which are required for the synthesis of DNA

of the study/trial Not applicable

Unmodified HLA-I is refolded with a placeholder peptide, then challenged with a dipeptide to displace the placeholder peptide, and finally loaded with the peptide of interest [18, 24]