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Participants experienced an average weight loss of 10-15% of their body weight over 68 weeks when using semaglutide alongside a healthy diet and exercise regimen

2026;49:413-423 - routine-care cohort, semaglutide arm n=1,393, -8.8% at 6 months

The technical term is long-term potentiation of sensory nerves, essentially an error in the way the nervous system processes and remembers pain signals

It prompts the body to release insulin, allowing cells to use glucose as an energy source, while reducing glucagon, a hormone that signals the liver to release stored glucose