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Since PWS is characterized by impaired hypothalamic regulation and neurodevelopmental anomalies in the satiety and reward regulating pathways, the question arises of whether GLP-1 RAs are effective and consistent in this population

Switching patients to a different medication sounds simple, but a research review in the American Journal of Therapeutics found that the consequences of switching a brand-name medication to a generic include: Decreased medication adherence Poorer clinical outcomes (e.g., symptom relief and overall health) An increase in adverse clinical outcomes, such as hospitalization and even death Ultimately, an Ozempic shortage increases the risk of harm to Type 2 diabetes patients who need this drug

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Dig Liver Dis