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Moreover, elderly pDCs are less capable of stimulating CD8 + T cells to produce perforin and granzyme, which are crucial for cytotoxic activity, and they are less efficient in promoting IFN- secretion by CD4 + and CD8 + T cells [258]
We acknowledge the limitations of our study
Abstract The plasma membrane protein caveolin-1 (CAV-1) regulates signaling by inhibiting a wide range of kinases and other enzymes