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doi: 10.1073/pnas.1321347111 116 CarreroJAMcCarthyDPFerrisSTWanXHuHZinselmeyerBHet al

Because skin cells turn over every 28 to 40 days, consistency is more important than a high "megadose" taken sporadically

You can also administer a loading dose this is a 1ml injection every second day for 3 injections total and then the normal dose of 1ml every 4 to 6 weeks

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[DOI] [PubMed] [Google Scholar] Ferrante KL, Shefner J, Zhang H, Betensky R, OBrien M, Yu H, Fantasia M, Taft J, Beal MF, Traynor B, Newhall K, Donofrio P, Caress J, Ashburn C, Freiberg B, ONeill C, Paladenech C, Walker T, Pestronk A, Abrams B, Florence J, Renna R, Schierbecker J, Malkus B, Cudkowicz M