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Shuxiao says people report symptoms including: Changes in vaginal discharge (including texture, smell, frequency) Vaginal dryness or itchiness Increased yeast or bacterial infections Loss of fullness or sagging in the vulvar area Feeling of pelvic floor weakness or loss of pubic fullness Changes in sensitivity or sex drive These symptoms arent listed as official Ozempic side effects , but they may occur indirectly as the body adjusts to weight loss, hormonal shifts, and microbiome changes