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In humans, the activity of BAT shows an inverse relationship with levels of adiposity, blood glucose, and insulin sensitivity (61, 70)

In addition, the inhibition of HDAC1 and HDAC2 alleviates glomerular sclerosis, interstitial fibrosis, and doxycycline-induced podocyte damage (Inoue et al., 2019)

Moreover, treatment with AST mitigated cytotoxicity, dysfunction of mitochondria, and oxidative stress induced by rotenone in a dose-dependent manner in SK-N-SH cells

When DRP1 was treated with KU-57788, the results showed that under the same temperature conditions, DRP1 protein degradation was significantly slower compared to untreated conditions (Fig