LDN is used off-label to support fibromyalgia, long COVID, MS, Crohns disease, rheumatoid arthritis, and chronic fatigue-related conditions
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High-fiber diets promote a healthy microbiome composition and have been shown to improve insulin sensitivity, reduce inflammation, and lower blood cholesterol levels
They adopted the following exclusion criteria: pregnancy, women with suspected pregnancy or breastfeeding
importantly, our data do not rule out other H4R-mediated pathways to neutrophil infiltration, such as an indirect effect on intestinal barrier function, but these mechanisms remain to be determined in future studies