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While recent incretin-based therapies have provided pharmaceutical inroads into treatment of obesity, there remains an ongoing need for additional medicines with distinct modes of action as independent or complementary therapeutics
Chronic Oxidative Stress (Depletes Glutathione Faster Than Its Made) Anything that increases free radical production depletes glutathione: Chronic inflammation (autoimmune diseases, obesity, metabolic syndrome) Environmental toxins (air pollution, pesticides, heavy metals) Alcohol consumption (glutathione is rapidly depleted in liver detoxification) Poor diet (high in processed foods, seed oils, sugar) Intense exercise (without adequate recovery) When oxidative stress exceeds your bodys capacity to recycle GSSG back to GSH, levels drop [4]
Nitric oxide in mucosal immunity
Glutathione is a chemical made from the amino acids glycine, cysteine, and glutamic acid
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