It is primarily cleared through receptor-mediated endocytosis and proteolytic degradation, not through hepatic CYP450 metabolism
Diabetes Obes Metab 13(5):426433 Becker RHA, Stechl J, Steinstraesser A, Golor G, Pellissier F (2015) Lixisenatide reduces postprandial hyperglycaemia via gastrostatic and insulinotropic effects
doi:10.1007/s00198-019-04853-7
Water, stabilizer polydextrose, acidity regulator citric acid, carbon dioxide, L-carnitine, taurine, flavouring, preservatives (potassium sorbate, sodium benzoate), sweetener acesulfame K, caffeine, sweetener sucralose, colouring azorubine may adversely affect activity and attention of children
De Simone R, Ajmone-Cat MA, Carnevale D, Minghetti L (2005) Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures