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Diabetologia 67(Suppl 1):abstract 81 Ali A, Khan D, Dubey V, Tarasov AI, Flatt PR, Irwin N (2024) Comparative effects of GLP-1 and GLP-2 on beta-cell function, glucose homeostasis and appetite regulation

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Discontinuation due to adverse events was reported as higher at the top dose than placebo

However, theres debate about their effectiveness: Oral GSH has limited bioavailability because it gets broken down in the digestive system

March 2, 2026: Gastrointestinal Lawsuits Involving Trulicity, Other GLP-1s Increase in March Eli Lilly and one other drug company are facing 3,363 lawsuits in a consolidated MDL, in which plaintiffs accuse the companies of failing to warn patients about the gastrointestinal risks of taking Trulicity and other GLP-1s