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We caution you that forward-looking statements are not guarantees of future performance and that our actual results may differ materially from those made in or suggested by the forward-looking statements contained in this communication

In essential hypertension, the independent, collective or interactive effects of insulin resistance, activation of RAS, decreased NO, or increased oxidative stress and AGEs on the kidneys may contribute to a decrease in kidney function, leading to elevations in blood pressure (27,28,82,83,214218)

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