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This allows CHAC1 to post-translationally regulate protein activity by binding and cleaving specific -glutamyl amino acids ( Although CHAC2 enzymes in Leishmania major were shown to degrade only reduced and not oxidized glutathione, this specificity has yet to be confirmed for CHAC1 (Das et al., 2022)

In post-mortem brain, out of 3 studies, 2 reported decreased GSH with age in hippocampal and frontal regions, while 1 study reported increased GSH with age in a frontal region

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On the following day, irradiation was repeated after the ingestion of 480 mg of Fernblock and 24 hours later they were assessed again using the same methods