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An overactive TCA cycle stresses the endoplasmic reticulum, thus inducing mitochondrial dysfunction and formation of reactive oxidative species and toxic lipid intermediates, like ceramides and diacylglycerol (22, 23)
Alterations in metabolite production in the gut, from either host or microbiota or their interaction, may be related to the manifestation of IBS symptoms
We welcome original research articles, review articles, and communications that focus on the dysregulation of immune pathways, cytokine networks, and genetic and epigenetic factors contributing to inflammation and tissue damage in rheumatic diseases
Can non-surgical treatments like RF microneedling replace surgery for loose skin after weight loss