As I followed up patients thought 2022 I realised there was a lot more going on with the medication then just exacerbating hangovers
Ideal candidates typically include: Adults with a BMI of 30 or higher (classified as obese) Adults with a BMI of 27 or higher who have at least one weight-related condition, such as type 2 diabetes, hypertension, high cholesterol, PCOS, or obstructive sleep apnea Individuals who have tried diet and exercise consistently but havent achieved meaningful weight loss Patients seeking a non-surgical, medication-based alternative to bariatric procedures People with insulin resistance, prediabetes, or blood sugar management challenges Semaglutide is not recommended for patients who are pregnant, breastfeeding, or planning to conceive, as well as those with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
Yao J, Zhu CQ, Sun Y, Huang YW, Li QH, Liao HM, Deng XJ, Li WM (2025) Insulin resistance: The role in comorbid type 2 diabetes mellitus and depression
Temperature fluctuations in that range accelerate degradation but do not immediately destroy bioactivity
Its no wonder that these peptides and similar agents are no longer the domain of just a few biohackers, but are edging into mainstream use without decent evidence