is it safe to get pregnant on tirzepatide Can the new diabetes and weight loss drugs affect reproductive health? — Those Nerdy Girls TrimRX | Tirzepatide and Pregnancy:

Tirzepatide has metabolic effects that go beyond appetite suppression

The medication reaches steady state By week four or five, semaglutide achieves steady-state pharmacokinetics

This timing leverages physiologic factors including reduced somatostatin inhibition during sleep, increased GHRH receptor sensitivity during evening hours, and optimal metabolic conditions supporting growth hormone synthesis and secretion, while morning or midday administration stimulates smaller daytime pulses with less consistent metabolic benefits

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Enhances Sperm Motility Motility helps sperm reach and fertilize the egg