J Biol Chem (2014) 289:191729
For many vitamins, this oral route is perfectly effective
67 Non-proliferative astrogliosis typically occurs in neural tissue that is responding to a pathology but is not overtly damaged and retains its basic tissue architecture, for example (i) during diffuse neuroinflammation caused by peripheral exposure to microbial antigens such as lipopolysaccharide (LPS), 68,69 (ii) in tissue regions that are at a distance from focal lesions (diaschisis) caused by stroke, trauma or autoimmune attack, 8,70 or (iii) in tissue undergoing neurodegenerative changes
At the level of microcircuits, this could be studied, e.g., by comparison of plasticity in feed-forward vs
Peer review Peer review information Nature Reviews Endocrinology thanks Michael Pollak and the other, anonymous, reviewer(s) for their contribution to the peer review of this work