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Human -synuclein aggregation activates ferroptosis leading to parvalbumin interneuron degeneration and motor learning impairment

Among the 13 studies reviewed, five used 1.5 T field strength ( At 1.5 T magnetic field strength, the ability to distinguish metabolites is particularly challenging due to the poorer separation of resonances in the spectra than at 3 or 7 T

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For lentiviral particles production, the full-length cDNA-encoding mito GCL, or its mutant inactive E103A form, was first digested with Eco 47III /Sma I to generate blunt ends, and then subcloned in the Pme I site of pWPI lentiviral vector (Didier Trono laboratory, Lausanne, Switzerland)

The incidences of bleeding were comparable in the 200 mg and 300 mg dosing regimens (3% in each group), but lower in contrast with enoxaparin (8%)