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Given the independent yet often overlapping mechanisms of action of both exercise and polyphenols, there is a compelling rationale for investigating their combined, synergistic effects in combating obesity

The authors compared these results to 4 historical published reports of early-onset Type 1 diabetes without GLP-1 drug intervention, and all those cohorts had increased HbA1c over time

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These models allow for a systematic investigation of the differential effects of peripheral ApoE isoforms on brain function and AD pathology [85]

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