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43:127-143 [PMC free article: PMC6470100] [PubMed: 30993937] 108

99,100 It is composed of a 1:2.5 ratio mixture of low molecular weight (80100 kDa) HA and low molecular weight CS (1020 kDa), dispersed in a bioadhesive carrier (Poloxamer 407)

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And they generally demonstrate favorable safety profiles compared to conventional immunosuppressants, though long-term data in autoimmune populations remains limited for most of these compounds