Similar to tirzepatide, semaglutide mimics the hormone GLP-1 and triggers the body to make more insulin when blood sugar levels rise after eating
Previous studies revealed that AST-120 contributes to changes in the gut microbiome composition, reduces ROS production from endothelial cells, and thus blocks the resultant oxidative stress and inflammation (121, 122)
Dig Dis Sci 2010;55(7):1824-1830
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Both medications share comparable safety profiles, with common gastrointestinal side effects including nausea, vomiting, diarrhea, and abdominal pain that are generally mild to moderate and resolve as the body adjusts