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The mitochondria are the powerhouses of cells, responsible for producing energy in the form of ATP

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This enzyme is localized into mitochondria and acts in two crucial pathways of the energetic metabolism, such as the Krebs cycle and the electron transport chain, by converting succinate into fumarate, together with the reduction of flavin adenine dinucleotide (FAD) into FADH 2

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Cardiovascular and mortality outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a meta-analysis with the FREEDOM cardiovascular outcomes trial