A method for preventing drug-induced ototoxicity in an individual in need thereof comprising intratympanic administration of a pharmaceutical composition comprising a therapeutic agent, wherein the therapeutic agent is an antioxidant or anti-apoptotic agent, wherein the pharmaceutical composition is administered prior to onset of therapy with the drug, and wherein the composition provides sustained release of the therapeutic agent into the ear for a period of at least 5 days after a single administration
The peptide appears to exert a protective effect through modulation of the dopaminergic and serotonergic systems, as well as through reduction of oxidative stress
How Acetyl L-Carnitine Fuels Brain Energy Role in Mitochondrial Function and Energy Metabolism Acetyl l-carnitine works by transporting fatty acids into these mitochondria, where they are converted into energy production
Gut-Brain Axis Gastroprotection Gastrointestinal Protection & Neuroprotection Protection of the gastric and intestinal mucosa: ulcers, colitis, NSAID lesions
mtDNA Mitochondrial transcription factor B2 (TFB2M) is a key protein involved in the regulation of mitochondrial DNA (mtDNA) transcription and compaction
