A small increase in heart rate can happen in some people
Endometriotic implants secrete estradiol (E2) as well as prostaglandin E2 (PGE2), agents that attract macrophages (monocyte chemotactic protein 1[MCP-1]), neurotrophic peptides (nerve growth factor [NGF]), enzymes for tissue remodeling (matrix metalloproteinases [MMPs]) and tissue inhibitors of MMPs (TIMPs), and proangiogenic substances such as vascular endothelial growth factor (VEGF) and interleukin-8 (6)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Kruk M.E., Gage A.D., Arsenault C., Jordan K., Leslie H.H., Roder-DeWan S., Adeyi O., Barker P., Daelmans B., Doubova S.V
Hossain, Role of Tirzepatide in Obesity Management Among Women with Polycystic Ovary Syndrome